研究業績

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  4. 2021年

2021年研究業績

英文総説

  1. Teshima T. Learning to mellow out GVHD. Blood. 2021 Mar 4;137(9):1142-1143. doi: 10.1182/blood.2020009315. PMID: 33661292
  2. Ara T, Hashimoto D. Novel Insights Into the Mechanism of GVHD-Induced Tissue Damage. Front Immunol. 2021 Aug 27;12:713631. doi: 10.3389/fimmu.2021.713631. eCollection 2021. PMID: 34512636
  3. Teshima T, Hill GR. The Pathophysiology and Treatment of Graft-Versus-Host Disease: Lessons Learnt From Animal Models. Front Immunol. 2021 Aug 19;12:715424. doi: 10.3389/fimmu.2021.715424. eCollection 2021. PMID: 34489966
  4. Murata M, Teshima T. Treatment of Steroid-Refractory Acute Graft-Versus-Host Disease Using Commercial Mesenchymal Stem Cell Products. Front Immunol. 2021 Aug 19;12:724380. doi: 10.3389/fimmu.2021.724380. eCollection 2021. PMID: 34489977
  5. Chakraverty R, Teshima T. Graft-versus-host disease: a disorder of tissue regeneration and repair. Blood. 2021 Nov 4;138(18):1657-1665. doi: 10.1182/blood.2021011867. PMID: 34370823
  6. Zeiser R, Teshima T. Nonclassical manifestations of acute GVHD. Blood. 2021 Dec 2;138(22):2165-2172. doi: 10.1182/blood.2021012431. PMID: 34482399

英文原著

  1. Nishiwaki S, Akahoshi Y, Mizuta S, Shinohara A, Hirabayashi S, Noguchi Y, Fukuda T, Uchida N, Tanaka M, Onizuka M, Ozawa Y, Ota S, Shiratori S, Onishi Y, Kanda Y, Sawa M, Tanaka J, Atsuta Y, Kako S. Measurable residual disease affects allogeneic hematopoietic cell transplantation in Ph+ ALL during both CR1 and CR2. Blood Adv. 2021 Jan 26;5(2):584-592. doi: 10.1182/bloodadvances.2020003536. PMID: 33496752
  2. Iwai T, Nishida M, Sugita J, Kudo Y, Takasugi R, Yokota I, Takagi R, Shibuya H, Takahashi S, Teshima T. Reliability of an ultrasonographical scoring system for diagnosis of sinusoidal obstruction syndrome/veno-occlusive disease in patients with hematopoietic stem cell transplantation. J Med Ultrason (2001). 2021 Jan;48(1):45-52. doi: 10.1007/s10396-020-01071-1. Epub 2021 Jan 4. PMID: 33398544
  3. Ueda N, Konuma T, Aoki J, Takahashi S, Ozawa Y, Mori T, Ota S, Eto T, Takada S, Yoshioka S, Shiratori S, Kako S, Onizuka M, Fukuda T, Kanda Y, Atsuta Y, Yanada M. Prognostic Impact of the Fractionation of Total Body Irradiation for Patients with Acute Myeloid Leukemia Undergoing Myeloablative Allogeneic Hematopoietic Cell Transplantation. Transplant Cell Ther. 2021 Feb;27(2):185.e1-185.e6. doi: 10.1016/j.jtct.2020.10.018. Epub 2020 Dec 13. PMID: 33830037
  4. Yamamoto M, Konno S, Makita H, Nitta K, Shimizu K, Suzuki M, Nishida M, Sugita J, Teshima T, Nishimura M. Factors for the Variability of Three Acceptable Maximal Expiratory Flow-Volume Curves in Chronic Obstructive Pulmonary Disease. Int J Chron Obstruct Pulmon Dis. 2021 Feb 24;16:415-422. doi: 10.2147/COPD.S285086. eCollection 2021. PMID: 33658773
  5. Taki K, Yokota I, Fukumoto T, Iwasaki S, Fujisawa S, Takahashi M, Negishi S, Hayasaka K, Sato K, Oguri S, Nishida M, Sugita J, Konno S, Saito T, Teshima T. SARS-CoV-2 detection by fluorescence loop-mediated isothermal amplification with and without RNA extraction. J Infect Chemother. 2021 Feb;27(2):410-412. doi: 10.1016/j.jiac.2020.10.029. Epub 2020 Oct 31. PMID: 33214073
  6. Yokota I, Hattori T, Shane PY, Konno S, Nagasaka A, Takeyabu K, Fujisawa S, Nishida M, Teshima T. Equivalent SARS-CoV-2 viral loads by PCR between nasopharyngeal swab and saliva in symptomatic patients. Sci Rep. 2021 Feb 24;11(1):4500. doi: 10.1038/s41598-021-84059-2. PMID: 33627730
  7. Fujimoto A, Anzai T, Fukuda T, Uchida N, Ohta T, Mori T, Sawa M, Yoshioka S, Miyamoto T, Uchiyama H, Katayama Y, Matsuoka KI, Shiratori S, Nakazawa H, Kanda J, Ichinohe T, Atsuta Y, Fujita N, Kondo E, Suzuki R. Impact of event-free survival status after stem cell transplantation on subsequent survival of patients with lymphoma. Blood Adv. 2021 Mar 9;5(5):1412-1424. doi: 10.1182/bloodadvances.2020003735. PMID: 33666656
  8. Kagami K, Ishiguro N, Yamada T, Niinuma Y, Iwasaki S, Taki K, Fukumoto T, Hayasaka K, Oyamada R, Watanabe T, Nishida M, Sugita J, Teshima T, Sugawara M, Takekuma Y. Efficacy and safety of colistin for the treatment of infections caused by multidrug-resistant gram-negative bacilli. J Infect Chemother. 2021 Mar;27(3):473-479. doi: 10.1016/j.jiac.2020.10.024. Epub 2020 Nov 2. PMID: 33144146
  9. Sugita J, Kamimura T, Ishikawa T, Ota S, Eto T, Kuroha T, Miyazaki Y, Kumagai H, Matsuo K, Akashi K, Taniguchi S, Harada M, Teshima T. Reduced dose of posttransplant cyclophosphamide in HLA-haploidentical peripheral blood stem cell transplantation. Bone Marrow Transplant. 2021 Mar;56(3):596-604. doi: 10.1038/s41409-020-01065-0. Epub 2020 Sep 24. PMID: 32973350
  10. Wakase S, Teshima T, Zhang J, Ma Q, Watanabe Y, Yang H, Qi CZ, Chai X, Xie Y, Wu EQ, Igarashi A. Cost-Effectiveness Analysis of Tisagenlecleucel for the Treatment of Pediatric and Young Adult Patients with Relapsed or Refractory B Cell Acute Lymphoblastic Leukemia in Japan. Transplant Cell Ther. 2021 Mar;27(3):241.e1-241.e11. doi: 10.1016/j.jtct.2020.12.023. Epub 2020 Dec 26. PMID: 33781519
  11. Nishida T, Kobayashi T, Sawa M, Masuda S, Shibasaki Y, Goto T, Fukuhara N, Fujii N, Ikegame K, Sugita J, Ikeda T, Kuwatsuka Y, Suzuki R, Najima Y, Doki N, Kato T, Inagaki Y, Utsu Y, Aotsuka N, Masuko M, Terakura S, Onishi Y, Maeda Y, Okada M, Teshima T, Murata M. A multicenter phase II study of intrabone single-unit cord blood transplantation without antithymocyte globulin. Ann Hematol. 2021 Mar;100(3):743-752. doi: 10.1007/s00277-020-04365-z. Epub 2021 Jan 11. PMID: 33427909
  12. Shiratori S, Ohigashi H, Ara T, Yasumoto A, Goto H, Nakagawa M, Sugita J, Onozawa M, Kahata K, Endo T, Hashimoto D, Teshima T. High lymphocyte counts before antithymocyte globulin administration predict acute graft-versus-host disease. Ann Hematol. 2021 May;100(5):1321-1328. doi: 10.1007/s00277-020-04347-1. Epub 2020 Nov 19. PMID: 33215225
  13. Sakurai M, Mori T, Kato K, Kanaya M, Mizuno S, Shiratori S, Wakayama T, Uchida N, Kobayashi H, Kubo K, Amano I, Ohta T, Miyazaki Y, Kanda J, Fukuda T, Atsuta Y, Kondo E; Adult Lymphoma Working Group of the Japan Society for Hematopoietic Cell Transplantation (JSHCT). Outcome of allogeneic hematopoietic stem cell transplantation for follicular lymphoma relapsing after autologous transplantation: analysis of the Japan Society for Hematopoietic Cell Transplantation. Bone Marrow Transplant. 2021 Jun;56(6):1462-1466. doi: 10.1038/s41409-020-01192-8. Epub 2021 Jan 29. PMID: 33514920
  14. Terakura S, Kuwatsuka Y, Sugita J, Takahashi S, Ozawa Y, Ozeki K, Yoshioka S, Nakamae H, Kawakita T, Sawa M, Morishige S, Najima Y, Katsuoka Y, Sakaida E, Kouzai Y, Kimura T, Ichinohe T, Fukuda T, Atsuta Y, Murata M, Teshima T. Effect of methotrexate dose in graft-versus-host disease prophylaxis after single-unit cord blood transplantation in adult acute myeloid leukemia. Int J Hematol. 2021 Jun;113(6):840-850. doi: 10.1007/s12185-021-03097-8. Epub 2021 Feb 21. PMID: 33611725
  15. Wakase S, Teshima T, Zhang J, Ma Q, Fujita T, Yang H, Chai X, Qi CZ, Liu Q, Wu EQ, Igarashi A. Cost Effectiveness Analysis of Tisagenlecleucel for the Treatment of Adult Patients with Relapsed or Refractory Diffuse Large B Cell Lymphoma in Japan. Transplant Cell Ther. 2021 Jun;27(6):506.e1-506.e10. doi: 10.1016/j.jtct.2021.03.005. Epub 2021 Mar 6. PMID: 33823168
  16. Nakamura M, Arai Y, Hirabayashi S, Kondo T, Doki N, Uchida N, Fukuda T, Ozawa Y, Tanaka M, Sawa M, Katayama Y, Kanda Y, Shiratori S, Nakamae H, Yoshioka S, Onizuka M, Ichinohe T, Atsuta Y, Kako S. Residual disease is a strong prognostic marker in patients with acute lymphoblastic leukaemia with chemotherapy-refractory or relapsed disease prior to allogeneic stem cell transplantation. Br J Haematol. 2021 Jul;194(2):403-413. doi: 10.1111/bjh.17646. Epub 2021 Jun 22. PMID: 34159580
  17. Nishida M, Sugita J, Takahashi S, Iwai T, Sato M, Kudo Y, Omotehara S, Horie T, Sakano R, Shibuya H, Yokota I, Iguchi A, Teshima T. Refined ultrasonographic criteria for sinusoidal obstruction syndrome after hematopoietic stem cell transplantation. Int J Hematol. 2021 Jul;114(1):94-101. doi: 10.1007/s12185-021-03137-3. Epub 2021 Mar 24. PMID: 33763826
  18. Zeiser R, Polverelli N, Ram R, Hashmi SK, Chakraverty R, Middeke JM, Musso M, Giebel S, Uzay A, Langmuir P, Hollaender N, Gowda M, Stefanelli T, Lee SJ, Teshima T, Locatelli F. Ruxolitinib for Glucocorticoid-Refractory Chronic Graft-versus-Host Disease. N Engl J Med. 2021 Jul 15;385(3):228-238. doi: 10.1056/NEJMoa2033122. PMID: 34260836
  19. Oguri S, Fujisawa S, Kamada K, Nakakubo S, Yamashita Y, Nakamura J, Horii H, Sato K, Nishida M, Teshima T, Ohiro Y, Takada A, Konno S. Effect of varying storage conditions on diagnostic test outcomes of SARS-CoV-2. J Infect. 2021 Jul;83(1):119-145. doi: 10.1016/j.jinf.2021.03.026. Epub 2021 Apr 3. PMID: 33823203
  20. Terui Y, Rai S, Izutsu K, Yamaguchi M, Takizawa J, Kuroda J, Ishikawa T, Kato K, Suehiro Y, Fukuhara N, Ohmine K, Goto H, Yamamoto K, Kanemura N, Ueda Y, Ishizawa K, Kumagai K, Kawasaki A, Saito T, Hashizume M, Shibayama H. A phase 2 study of polatuzumab vedotin + bendamustine + rituximab in relapsed/refractory diffuse large B-cell lymphoma. Cancer Sci. 2021 Jul;112(7):2845-2854 PMID: 33942442
  21. Akahoshi Y, Kimura SI, Inamoto Y, Seo S, Muranushi H, Shimizu H, Ozawa Y, Tanaka M, Uchida N, Kanda Y, Katayama Y, Shiratori S, Ota S, Matsuoka KI, Onizuka M, Fukuda T, Atsuta Y, Murata M, Terakura S, Nakasone H. Effect of Cytomegalovirus Reactivation With or Without Acute Graft-Versus-Host Disease on the Risk of Nonrelapse Mortality. Clin Infect Dis. 2021 Aug 2;73(3):e620-e628. doi: 10.1093/cid/ciaa1871. PMID: 33341890
  22. Yokota I, Sakurazawa T, Sugita J, Iwasaki S, Yasuda K, Yamashita N, Fujisawa S, Nishida M, Konno S, Teshima T. Performance of Qualitative and Quantitative Antigen Tests for SARS-CoV-2 Using Saliva. Infect Dis Rep. 2021 Aug 24;13(3):742-747. doi: 10.3390/idr13030069. PMID: 34449650
  23. Eguchi S, Egawa H, Eguchi H, Uehira T, Endo T, Genda T, Shinoda M, Hasegawa K, Shimamura T, Tsukada K, Hara T, Nakao K, Yatsuhashi H, Yotsuyanagi H, Natsuda K, Soyama A, Hidaka M, Hara T, Takatsuki M. Indications and waiting list priority for deceased donor liver transplantation in HIV/HCV co-infected hemophilic patients in Japan through contaminated blood product. Hepatol Res. 2021 Aug;51(8):909-914. doi: 10.1111/hepr.13686. Epub 2021 Jun 26. PMID: 34132462
  24. Yokota I, Shane PY, Okada K, Unoki Y, Yang Y, Inao T, Sakamaki K, Iwasaki S, Hayasaka K, Sugita J, Nishida M, Fujisawa S, Teshima T. Mass Screening of Asymptomatic Persons for Severe Acute Respiratory Syndrome Coronavirus 2 Using Saliva. Clin Infect Dis. 2021 Aug 2;73(3):e559-e565. doi: 10.1093/cid/ciaa1388. PMID: 32976596
  25. Teshima T, Yuchi Y, Suzuki R, Matsumoto H, Koyama H. Immunomodulatory Effects of Canine Adipose Tissue Mesenchymal Stem Cell-Derived Extracellular Vesicles on Stimulated CD4+ T Cells Isolated from Peripheral Blood Mononuclear Cells. J Immunol Res. 2021 Aug 14;2021:2993043. doi: 10.1155/2021/2993043. eCollection 2021. PMID: 34447855
  26. Yokota I, Shane PY, Okada K, Unoki Y, Yang Y, Iwasaki S, Fujisawa S, Nishida M, Teshima T. A novel strategy for SARS-CoV-2 mass screening with quantitative antigen testing of saliva: a diagnostic accuracy study. Lancet Microbe. 2021 Aug;2(8):e397-e404. doi: 10.1016/S2666-5247(21)00092-6. Epub 2021 May 19. PMID: 34031649
  27. Kurosawa S, Yamaguchi T, Mori A, Matsuura T, Mori T, Tanaka M, Kondo T, Umemoto Y, Goto H, Yoshioka S, Machida S, Sato T, Katayama Y, Kato S, Shono K, Mizuno I, Fujiwara S, Kohno A, Takanashi M, Fukuda T. Resignation and return to work in patients receiving allogeneic hematopoietic cell transplantation. J Cancer Surviv. 2021 Aug 27. doi: 10.1007/s11764-021-01092-w.esi. Online ahead of print. PMID: 34449050
  28. Shiratori S, Sugita J, Fuji S, Aoki J, Sawa M, Ozawa Y, Hashimoto D, Matsuoka KI, Imada K, Doki N, Ashida T, Ueda Y, Tanaka M, Sawayama Y, Ichinohe T, Terakura S, Morishima S, Atsuta Y, Fukuda T, Teshima T. Low-dose antithymocyte globulin inhibits chronic graft-versus-host disease in peripheral blood stem cell transplantation from unrelated donors. Bone Marrow Transplant. 2021 Sep;56(9):2231-2240. doi: 10.1038/s41409-021-01314-w. Epub 2021 May 7. PMID: 33963304
  29. Fujii Y, Asakura S, Takanobu K, Watanabe S, Toyoshima K, Mitsui N, Kako Y, Hashino S, Kusumi I. Prevalence of depressive symptoms and psychological distress in Japanese university-enrolled students before and during the coronavirus disease 2019 pandemic. Psychiatry Clin Neurosci. 2021 Sep;75(9):294-295. doi: 10.1111/pcn.13287. Epub 2021 Jul 28. PMID: 34231285
  30. Izutsu K, Ando K, Nishikori M, Shibayama H, Teshima T, Kuroda J, Kato K, Imaizumi Y, Nosaka K, Sakai R, Hojo S, Nakanishi T, Rai S. Phase II study of tazemetostat for relapsed or refractory B-cell non-Hodgkin lymphoma with EZH2 mutation in Japan. Cancer Sci. 2021 Sep;112(9):3627-3635. doi: 10.1111/cas.15040. Epub 2021 Jul 14. PMID: 34159682
  31. Yokota I, Shane PY, Teshima T. Logistic advantage of two-step screening strategy for SARS-CoV-2 at airport quarantine. Travel Med Infect Dis. 2021 Sep-Oct;43:102127. doi: 10.1016/j.tmaid.2021.102127. Epub 2021 Jun 23. PMID: 34174408
  32. Doki N, Toyosaki M, Shiratori S, Osumi T, Okada M, Kawakita T, Sawa M, Ishikawa T, Ueda Y, Yoshinari N, Nakahara S. An Open-Label, Single-Arm, Multicenter Study of Ibrutinib in Japanese Patients With Steroid-dependent/Refractory Chronic Graft-Versus-Host Disease. Transplant Cell Ther. 2021 Oct;27(10):867.e1-867.e9. doi: 10.1016/j.jtct.2021.05.019. Epub 2021 Jun 6. PMID: 34102349
  33. Ito A, Nakano N, Tanaka T, Fuji S, Makiyama J, Inoue Y, Choi I, Nakamae H, Nagafuji K, Takase K, Machida S, Takahashi T, Sawayama Y, Kamimura T, Kato K, Kawakita T, Ogata M, Sakai R, Shiratori S, Uchimaru K, Inamoto Y, Utsunomiya A, Fukuda T. Improved survival of patients with aggressive ATL by increased use of allo-HCT: a prospective observational study. Blood Adv. 2021 Oct 26;5(20):4156-4166. doi: 10.1182/bloodadvances.2021004932. PMID: 34500464
  34. Ono S, Takeshita K, Kiridoshi Y, Kato M, Kamiya T, Hoshino A, Yanagimachi M, Arai K, Takeuchi I, Toita N, Imamura T, Sasahara Y, Sugita J, Hamamoto K, Takeuchi M, Saito S, Onuma M, Tsujimoto H, Yasui M, Taga T, Arakawa Y, Mitani Y, Yamamoto N, Imai K, Suda W, Hattori M, Ohara O, Morio T, Honda K, Kanegane H. Hematopoietic Cell Transplantation Rescues Inflammatory Bowel Disease and Dysbiosis of Gut Microbiota in XIAP Deficiency. J Allergy Clin Immunol Pract. 2021 Oct;9(10):3767-3780. doi: 10.1016/j.jaip.2021.05.045. Epub 2021 Jul 8. PMID: 34246792
  35. Wolff D, Radojcic V, Lafyatis R, Cinar R, Rosenstein RK, Cowen EW, Cheng GS, Sheshadri A, Bergeron A, Williams KM, Todd JL, Teshima T, Cuvelier GDE, Holler E, McCurdy SR, Jenq RR, Hanash AM, Jacobsohn D, Santomasso BD, Jain S, Ogawa Y, Steven P, Luo ZK, Dietrich-Ntoukas T, Saban D, Bilic E, Penack O, Griffith LM, Cowden M, Martin PJ, Greinix HT, Sarantopoulos S, Socie G, Blazar BR, Pidala J, Kitko CL, Couriel DR, Cutler C, Schultz KR, Pavletic SZ, Lee SJ, Paczesny S. National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: IV. The 2020 Highly morbid forms report. Transplant Cell Ther. 2021 Oct;27(10):817-835. doi: 10.1016/j.jtct.2021.06.001. Epub 2021 Jun 10. PMID: 34217703
  36. Schuster SJ, Tam CS, Borchmann P, Worel N, McGuirk JP, Holte H, Waller EK, Jaglowski S, Bishop MR, Damon LE, Foley SR, Westin JR, Fleury I, Ho PJ, Mielke S, Teshima T, Janakiram M, Hsu JM, Izutsu K, Kersten MJ, Ghosh M, Wagner-Johnston N, Kato K, Corradini P, Martinez-Prieto M, Han X, Tiwari R, Salles G, Maziarz RT. Long-term clinical outcomes of tisagenlecleucel in patients with relapsed or refractory aggressive B-cell lymphomas (JULIET): a multicentre, open-label, single-arm, phase 2 study. Lancet Oncol. 2021 Oct;22(10):1403-1415. doi: 10.1016/S1470-2045(21)00375-2. Epub 2021 Sep 10. PMID: 34516954
  37. Shima T, Sakoda T, Henzan T, Kunisaki Y, Sugio T, Kamezaki K, Iwasaki H, Teshima T, Maeda T, Akashi K, Miyamoto T. Platelet decrease and efficacy of platelet-rich plasma return following peripheral blood stem cell apheresis. J Clin Apher. 2021 Oct;36(5):687-696. doi: 10.1002/jca.21917. Epub 2021 Jun 16. PMID: 34133767
  38. Murata M, Terakura S, Wake A, Miyao K, Ikegame K, Uchida N, Kataoka K, Miyamoto T, Onizuka M, Eto T, Doki N, Ota S, Sato M, Hashii Y, Ichinohe T, Fukuda T, Atsuta Y, Okamoto S, Teshima T. Off-the-shelf bone marrow-derived mesenchymal stem cell treatment for acute graft-versus-host disease: real-world evidence. Bone Marrow Transplant. 2021 Oct;56(10):2355-2366. doi: 10.1038/s41409-021-01304-y. Epub 2021 May 11. PMID: 33976381
  39. Konuma T, Kondo T, Masuko M, Shimizu H, Shiratori S, Fukuda T, Kato J, Sawa M, Ozawa Y, Ota S, Uchida N, Kanda Y, Kako S, Fujisawa S, Fukushima K, Ichinohe T, Atsuta Y, Yanada M; Adult Acute Myeloid Leukemia Working Group of the Japan Society for Hematopoietic Cell Transplantation. Prognostic value of measurable residual disease at allogeneic transplantation for adults with core binding factor acute myeloid leukemia in complete remission. Bone Marrow Transplant. 2021 Nov;56(11):2779-2787. doi: 10.1038/s41409-021-01409-4. Epub 2021 Jul 16. PMID: 34272486
  40. Akahoshi Y, Arai Y, Nishiwaki S, Tachibana T, Shinohara A, Doki N, Uchida N, Tanaka M, Kanda Y, Shiratori S, Ozawa Y, Shono K, Katayama Y, Tanaka J, Fukuda T, Atsuta Y, Kako S. Newly proposed threshold and validation of white blood cell count at diagnosis for Philadelphia chromosome-positive acute lymphoblastic leukemia: risk assessment of relapse in patients with negative minimal residual disease at transplantation-a report from the Adult Acute Lymphoblastic Leukemia Working Group of the JSTCT. Bone Marrow Transplant. 2021 Nov;56(11):2842-2848. doi: 10.1038/s41409-021-01422-7. Epub 2021 Jul 30. PMID: 34331021
  41. Inoue T, Koyama M, Kaida K, Ikegame K, Ensbey KS, Samson L, Takahashi S, Zhang P, Minnie SA, Maruyama S, Ishii S, Daimon T, Fukuda T, Nakamae H, Ara T, Maruyama Y, Ishiyama K, Ichinohe T, Atsuta Y, Blazar BR, Furlan SN, Ogawa H, Hill GR. Peritransplant glucocorticoids redistribute donor T cells to the bone marrow and prevent relapse after haploidentical SCT. JCI Insight. 2021 Nov 22;6(22):e153551. doi: 10.1172/jci.insight.153551. PMID: 34637399
  42. Shimura T, Abe K, Takenouchi T, Yamada M, Suzuki H, Suematsu M, Nakakubo S, Kamada K, Konno S, Teshima T, Kosaki K. Multiple introductions of SARS-CoV-2 B.1.1.214 lineages from mainland Japan preceded the third wave of the COVID-19 epidemic in Hokkaido. Travel Med Infect Dis. 2021 Nov-Dec;44:102210. doi: 10.1016/j.tmaid.2021.102210. Epub 2021 Nov 22. PMID: 34822976
  43. Kimura SI, Tamaki M, Okinaka K, Seo S, Uchida N, Igarashi A, Ozawa Y, Ikegame K, Eto T, Tanaka M, Shiratori S, Nakamae H, Sawa M, Kawakita T, Onizuka M, Fukuda T, Atsuta Y, Kanda Y, Nakasone H. Cytomegalovirus reactivation is associated with an increased risk of late-onset invasive aspergillosis independently of grade II-IV acute graft-versus-host disease in allogeneic hematopoietic stem cell transplantation: JSTCT Transplant Complications Working Group. Ann Hematol. 2021 Dec;100(12):3029-3038. doi: 10.1007/s00277-021-04660-3. Epub 2021 Sep 7. PMID: 34490500
  44. Kagami K, Ishiguro N, Yamada T, Niinuma Y, Iwasaki S, Taki K, Fukumoto T, Hayasaka K, Nishida M, Sugita J, Teshima T, Sugawara M, Takekuma Y. Clinical outcomes of intervention for carbapenems and anti-methicillin-resistant Staphylococcus aureus antibiotics by an antimicrobial stewardship team. Am J Infect Control. 2021 Dec;49(12):1493-1498. doi: 10.1016/j.ajic.2021.08.011. Epub 2021 Aug 17. PMID: 34416316
  45. Shiratori S, Kurata M, Sugita J, Ota S, Kasahara S, Ishikawa J, Imada K, Onishi Y, Ishiyama K, Ashida T, Kanda Y, Ichinohe T, Fukuda T, Atsuta Y, Teshima T. Graft-Versus-Host Disease Prophylaxis Using Low-Dose Antithymocyte Globulin in Peripheral Blood Stem Cell Transplantation-A Matched-Pair Analysis. Transplant Cell Ther. 2021 Dec;27(12):995.e1-995.e6. doi: 10.1016/j.jtct.2021.08.029. Epub 2021 Sep 6. PMID: 34500126
  46. Fowler NH, Dickinson M, Dreyling M, Martinez-Lopez J, Kolstad A, Butler J, Ghosh M, Popplewell L, Chavez JC, Bachy E, Kato K, Harigae H, Kersten MJ, Andreadis C, Riedell PA, Ho PJ, Pérez-Simón JA, Chen AI, Nastoupil LJ, von Tresckow B, Ferreri AJM, Teshima T, Patten PEM, McGuirk JP, Petzer AL, Offner F, Viardot A, Zinzani PL, Malladi R, Zia A, Awasthi R, Masood A, Anak O, Schuster SJ, Thieblemont C. Tisagenlecleucel in adult relapsed or refractory follicular lymphoma: the phase 2 ELARA trial. Nat Med. 2021 Dec 17. doi: 10.1038/s41591-021-01622-0. Online ahead of print. PMID: 34921238
  47. Yanada M, Mizuno S, Yamasaki S, Harada K, Konuma T, Tamaki H, Shingai N, Uchida N, Ozawa Y, Tanaka M, Onizuka M, Sawa M, Nakamae H, Shiratori S, Matsuoka KI, Eto T, Kawakita T, Maruyama Y, Ichinohe T, Kanda Y, Atsuta Y, Aoki J, Yano S. Difference in outcomes following allogeneic hematopoietic cell transplantation for patients with acute myeloid leukemia and myelodysplastic syndromes. Leuk Lymphoma. 2021 Dec;62(14):3411-3419. doi: 10.1080/10428194.2021.1961242. PMID: 34348554
  48. Kikuchi K, Komachi T, Honma Y, Endo T, Watabe K, Yokomaku Y, Hashiba C, Yamamoto M, Nagayo Y, Ito T, Imamura J, Suzuki T, Fujitani J. Survey of motor function and activities of daily living in hemophilia patients with HIV. GHM Open - Advance Publication. DOI: 10.35772/ghmopen.2021.01007
  49. Mitani A, Iwai T, Shichinohe T, Takeda H, Kumagai S, Nishida M, Sugita J, Teshima T. The Combined Usage of the Global Leadership Initiative on Malnutrition Criteria and Controlling Nutrition Status Score in Acute Care Hospitals. Ann Nutr Metab. 2021;77(3):178-184. doi: 10.1159/000516994. Epub 2021 Jul 16. PMID: 34274929

英文症例報告

  1. Suto K, Sugita J, Hashimoto D, Kameda H, Mitsuhashi T, Teshima T. Extramedullary hematopoiesis of the cranial dura. Int J Hematol. 2021 Mar;113(3):315-317. doi: 10.1007/s12185-020-03057-8. Epub 2021 Jan 5. PMID: 33400142
  2. Otagiri S, Nakajima S, Katsurada T, Sakurai K, Yamanashi K, Ara T, Takakuwa E, Mitsuhashi T, Sakamoto N. Chronic Diarrhea as the Presenting Feature of Amyloidosis with Multiple Myeloma: A Case Report Diagnosed by a Myocardial Biopsy. Intern Med. 2021 Apr 15;60(8):1197-1203. doi: 10.2169/internalmedicine.6038-20. Epub 2020 Nov 16. PMID: 33191327
  3. Shimizu M, Shimbo A, Takagi M, Eguchi K, Ishimura M, Sugita J, Morio T, Kanegane H. Successful treatment of joint and fascial chronic graft-versus-host disease with baricitinib. Rheumatology (Oxford). 2021 Jul 24:keab599. doi: 10.1093/rheumatology/keab599. Online ahead of print. PMID: 34302457
  4. Omotehara S, Nishida M, Yamanashi K, Sakurai K, Katsurada T, Komatsu Y, Shimizu A, Shibuya H, Shinagawa N, Sugita J, Teshima T. A case of immune checkpoint inhibitor-associated gastroenteritis detected by ultrasonography. J Clin Ultrasound. 2021 Jul;49(6):605-609. doi: 10.1002/jcu.22975. Epub 2021 Feb 12. PMID: 33580597
  5. Miyashita N, Onozawa M, Suto K, Fujisawa S, Okazaki N, Hidaka D, Ohigashi H, Yasumoto A, Sugita J, Hashimoto D, Matsuno Y, Teshima T. Aleukemic Extramedullary Blast Crisis as an initial presentation of Chronic Myeloid Leukemia with E1A3 BCR-ABL1 Fusion Transcript. Intern Med. 2021 Sep 11. doi: 10.2169/internalmedicine.8319-21. Online ahead of print. PMID: 34511573
  6. Tsutsumi Y, Ito S, Nagai J, Tateno T, Teshima T. Patients with marginal zone dural lymphoma successfully treated with rituximab and bendamustine: A report of two cases. Mol Clin Oncol. 2021 Oct;15(4):208. doi: 10.3892/mco.2021.2371. Epub 2021 Aug 9. PMID: 34466224
  7. Kondo T, Onozawa M, Fujisawa S, Harada S, Ogasawara R, Izumiyama K, Saito M, Morioka M, Mori A, Teshima T. Myelomonocytic differentiation of leukemic blasts accompanied by differentiation syndrome in a case of FLT3-ITD-positive AML treated with gilteritinib. Hematology. 2021 Dec;26(1):256-260. doi: 10.1080/16078454.2021.1889111. PMID: 33631087

和文総説

  1. Antithymocyte globulin for GVHD prophylaxis in allogeneic hematopoietic stem cell transplantation.
    Author:白鳥聡一(北海道大学 大学院医学研究院血液内科学教室)
    Source:Rinsho Ketsueki. 2021;62(8):1265-1274. doi: 10.11406/rinketsu.62.1265.
  2. 移植後シクロホスファミドを用いたHLA半合致移植後のcytokine release syndrome(総説)
    Author:杉田純一(北海道大学 大学院医学研究院血液内科学教室)
    Source:日本造血細胞移植学会雑誌 (2186-5612)10巻1号 Page66-71(2021.01)
  3. 【口腔とウイルス~疾患との関連から検査・感染予防対策まで~】COVID-19における唾液検査の有用性と今後の展望(解説/特集)
    Author:豊嶋崇徳(北海道大学 医学研究院血液内科)
    Source:歯科医療(0916-8842)35巻1号 Page33-39(2021.01)
  4. 急性GVHDの病態(解説/特集)
    Author:橋本大吾(北海道大学大学院医学研究院 血液内科)
    Source:炎症と免疫(0918-8371)29巻2号 Page137-142(2021.02)
  5. 【病気とくすり2021 基礎と実践Expert's Guide】免疫・炎症・アレルギーおよび骨・関節の病気とくすり 免疫・炎症・アレルギー疾患 移植片対宿主病(解説/特集)
    Author:豊嶋崇徳(北海道大学 大学院医学研究院内科系部門内科学分野血液内科学教室),久保田康生
    Source:薬局(0044-0035)72巻4号 Page810-825(2021.03)
  6. 【令和時代の総合内科学】遺伝子治療・細胞治療の将来 遺伝子改変T細胞(CAR-T)療法(解説/特集)
    Author:豊嶋崇徳(北海道大学 大学院医学研究院血液内科)
    Source:日本内科学会雑誌(0021-5384)110巻3号 Page414-419(2021.03)
  7. 【「COVID-19の現状と将来展望」】唾液によるコロナ診断法(解説/特集)
    Author:豊嶋崇徳(北海道大学 大学院医学研究院血液内科学教室)
    Source:日本染色体遺伝子検査学会雑誌(1884-3026)39巻1号 Page17-20(2021.06)
  8. 【がんのリハビリテーション-成果と展望】(第1章)がん治療最前線 造血幹細胞移植(解説/特集)
    Author:荒 隆英(北海道大学 大学院医学研究科内科系部門内科学分野血液内科学),豊嶋崇徳
    Source:Journal of Clinical Rehabilitation (0918-5259)30巻7号 Page687-691(2021.06)
  9. 【リンパ腫診療-診断の入り口から治療まで】リンパ腫に対するCAR-T療法(解説/特集)
    Author:後藤秀樹(北海道大学 大学院医学研究院血液内科学教室),豊嶋崇徳
    Source:内科(0022-1961)128巻2号 Page293-295(2021.08)
  10. 高用量DPP-4阻害薬を用いた同種造血幹細胞移植後の移植片対宿主病予防(解説)
    Author:橋本大吾(北海道大学大学院医学研究院 血液内科)
    Source:血液内科(2185-582X)83巻2号 Page270-274(2021.08)

和文症例報告

  1. 急性前骨髄球性白血病に対する同種造血幹細胞移植27年後に発症したドナー細胞由来未分化大細胞リンパ腫の1例
    Author:菊池 遼,(北海道大学大学院医学研究院 血液内科)小野澤真弘,今本鉄平,高橋秀一郎,杉田純一,橋本大吾,橋野 聡,松野吉宏,豊嶋崇徳
    Source:日本内科学会雑誌(0021-5384)110巻1号 Page92-98(2021.01)
  2. 経過中にcolony-stimulating factor 3 receptor遺伝子変異が出現した骨髄増殖性腫瘍-分類不能型
    Author:原田晋平(北海道大学 血液内科),岡田耕平,横山翔大,日高大輔,早瀬英子,小野澤真弘,後藤秀樹,橋本大吾,加畑 馨,遠藤知之,豊嶋崇徳
    Source:臨床血液(0485-1439)62巻11号 Page1609-1614(2021.06)

和文著書

  1. 〈雑誌〉白鳥聡一
    誌名:EBM血液疾患の治療 2021-2022
    Title:ATGによるGVHD予防の長期予後への影響 2021年1月
  2. 〈教科書〉遠藤知之 他12名
    書名:抗HIV治療ガイドライン
    Title:急性HIV感染症とその治療 2021年3月
  3. 〈雑誌〉荒 隆英,橋本大吾,豊嶋崇徳
    誌名:Japanese Scientists in Science Translational Medicine
    Title:大腸杯細胞はLypd8を介して同種造血幹細胞移植後のGVHDを防ぐ 2021年3月
  4. 〈雑誌〉後藤秀樹
    誌名:血液内科 vol.82 No.2 p231-235(科学評論社)
    Title:マントル細胞リンパ腫へのCAR-T療法 2021年3月
  5. 〈教科書〉橋本大吾,小野澤真弘,杉田純一,後藤秀樹,白鳥聡一
    書名:造血細胞移植看護基礎テキスト
    Title:造血幹細胞移植の基礎知識 2021年6月
  6. 〈雑誌〉荒 隆英,豊嶋崇徳
    誌名:JOURNAL OF CLINICAL REHABILITATION 臨時増刊号 がんとリハビリテーション-成果と展望
    Title:造血幹細胞移植 2021年6月
  7. 〈雑誌〉加畑 馨
    誌名:医学のあゆみ(0039-2359)277巻10号 Page850-854(2021.06)
    Title:【CAR-T細胞療法の現在と将来展望】CAR-T細胞治療のための施設要件と品質管理システムの構築 2021年6月
  8. 〈雑誌〉後藤秀樹
    誌名:医学のあゆみ vol.277 No.10 p920-926(医歯薬出版株式会社)
    Title:サイトカイン放出症候群 2021年6月
  9. 〈雑誌〉後藤秀樹
    誌名:診断と治療 vol.109 No.6 p843-847(診断と治療社)
    Title:CAR-T細胞療法 2021年6月
  10. 〈教科書〉橋本大吾
    書名:造血細胞移植看護基礎テキスト
    Title:第1章4. 移植免疫 2021年7月
  11. 〈教科書〉後藤秀樹
    書名:造血細胞移植看護基礎テキスト p2-7(日本造血・免疫細胞療法学会)
    Title:正常細胞のしくみ 2021年7月
  12. 〈教科書〉加畑 馨
    書名:細胞治療認定管理師制度指定カリキュラム
    Title:CAR(キメラ受容体)を用いた遺伝子免疫療法 2021年8月
  13. 〈雑誌〉後藤秀樹
    誌名:リンパ腫の診療update vol.79 No.3 p411-416 (南江堂)
    Title:免疫療法の展開 2021年8月
  14. 〈雑誌〉後藤秀樹,豊嶋崇徳
    誌名:内科 vol.128 No.2 p293-295(南江堂)
    Title:リンパ腫に対するCAR-T療法 2021年8月
  15. 〈教科書〉遠藤知之 他22名
    書名:HIV感染症「治療の手引き」
    2021/11/1
  16. 〈雑誌〉杉田純一
    誌名:血液内科 第83巻第5号 Page674-680
    Title:HLA半合致移植とHLA適合非血縁者間移植の比較 2021年11月
  17. 〈雑誌〉後藤秀樹
    誌名:ヘマトパセオ online ahead of print
    Title:再発難治性B-ALLに対するCAR-T療法の現状と課題 2021年11月